Journal: Indian Journal of Nuclear Medicine : IJNM : The Official Journal of the Society of Nuclear Medicine, India

Article Title: Validation of Quality Control Parameters of Cassette-Based Gallium-68-DOTA-Tyr3-Octreotate Synthesis

doi: 10.4103/ijnm.IJNM_66_20

Figure Lengend Snippet: Synthesis scheme of automated Scintomics module GRP ® to produce gallium-68-DOTA-Tyr3-octreotate

Article Snippet: Elution process is performed using a 0.1 M HCl solution (Rotem GmbH, Germany) driven by the GRP™ Interface software (Scintomics GRP ® , Fürstenfeldbruck, Germany) in approximately 5 min.

Techniques:

Journal: EJNMMI Radiopharmacy and Chemistry

Article Title: Automated synthesis of [ 68 Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

doi: 10.1186/s41181-022-00172-1

Figure Lengend Snippet: A. Setup for the production of [ 68 Ga]Ga-FAPI-46 on GallElut Scintomics synthesizer, and (B) Scheme of the synthesis module

Article Snippet: The GallElut Scintomics module (operated by the software ScintomicsTM (Scintomics GmbH, Fürstenfeldbruck, Germany)) shown in Fig. was also used for the automated synthesis of [ 68 Ga]Ga-FAPI-46 with a customized synthesis system.

Techniques:

Journal: The Journal of Biological Chemistry

Article Title: Mechanism of premature translation termination on a sense codon

doi: 10.1074/jbc.AW118.003232

Figure Lengend Snippet: Cryo-EM data collection and refinement statistics

Article Snippet: The different positions of domain 1 in different structures highlight that interactions between domain 1 and the ribosome are dynamic and are likely important at early stages of RF1 binding or during RF1 dissociation, in keeping with functional interaction between RF1 and L11 ( 27 , – 29 ). table ft1 table-wrap mode="anchored" t5 caption a7 Data collection EM equipment FEI Talos Arctica Voltage (kV) 200 Detector Gatan K2 Summit Software SerialEM Pixel size (Å) 0.944 Electron dose (e − /Å 2 ) 37.7 (used 19) Defocus range (μm) −0.7 to −1.7 Data set size (no. of particles) 1,065,147 Reconstruction Software cisTEM and Frealign versions 9.10 and 9.11 No. of particles used 639,088 Final resolution (Å, FSC = 0.143) 3.7 Model composition Nonhydrogen atoms 152,439 Protein residues 6520 RNA bases 4728 Refinement Software RSRef and Phenix Correlation coefficient 0.86 R -factor 0.186 Ramachandran-plot statistics (%) Favored (overall) 86.8 Allowed (overall) 12.4 Outlier (overall) 0.9 Rotamer outliers (%) 0.02 C-β deviations 0 Root mean square deviations Bond length (Å) 0.005 Bond angle (°) 0.84 Open in a separate window Cryo-EM data collection and refinement statistics Density in the peptidyl transferase and decoding centers ( , D and E ) showed interactions similar to those found in canonical termination complexes with RF1 ( 7 , 9 ).

Techniques: Software